growth customer messaging automation founded 2012 · 300-400 people · Portland, OR
saas data adtech marketplace enterprise
Customer.io is a behavioral messaging and marketing-automation platform that lets teams build data-driven email, push, and in-app campaigns off first-party event data. Its customers are product and marketing teams (8,000+ paying customers). It is a capital-efficient, largely distributed company that is HQ'd in Portland and crossed $100M ARR profitably.
Latest round: $35M series-a (2022) · $40.3M total raised
Leadership: Colin Nederkoorn (CEO)
growth legal governance, risk & compliance (GRC) software founded 2004 · Portland, OR
saas compliance security data enterprise govtech
Exterro sells a legal GRC platform spanning e-discovery, data privacy, digital forensics, and cybersecurity compliance for corporate legal, IT, and security teams. It serves 3,000+ customers including many Fortune 500 companies. It is a Portland-HQ'd unicorn (private) with a real local engineering org; it acquired fellow Portland firm Zapproved in 2023.
Latest round: growth (2022) · led by Leeds Equity Partners
Leadership: Bobby Balachandran (Founder & CEO)
growth identity / eligibility verification for marketing founded 2011 · 150-200 people · Portland, OR
saas data security ai enterprise
SheerID runs an enterprise identity/eligibility-verification platform that lets brands instantly and securely confirm a shopper belongs to a gated group (student, military, teacher, first responder) so they can extend targeted offers without fraud. Customers are enterprise marketing/growth teams (Amazon, Spotify, T-Mobile). Mid-size Portland-HQ'd SaaS org with multi-continent staff.
Latest round: $64M growth (2019) · led by CVC Growth Partners · $96M total raised
Founders: Jake Weatherly, David Shear
Leadership: Stephanie Copeland Weber (CEO)
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public generative AI drug creation founded 2011 · Vancouver, WA
ai ml data healthtech cloud
AbSci is a generative-AI drug-creation company that combines AI models with a synthetic-biology data engine and wet-lab validation to design biologic drug candidates. Its 'customers' are pharma partners (e.g., Almirall) plus its own pipeline. It has a substantial AI/data engineering arm alongside its lab, HQ'd in Vancouver, WA within the Portland metro.
public digital watermarking & product digitization founded 1994 · 200-250 people · Beaverton, OR
saas data security ai enterprise
Digimarc makes digital-watermarking software that embeds machine-readable identifiers into packaging, labels, images, and digital content for authentication, recycling, and anti-counterfeiting. Its customers are retailers, consumer brands, and government agencies. It is a Beaverton-HQ'd public company (Nasdaq: DMRC) with a local engineering org.
public long-duration iron flow batteries founded 2011 · Wilsonville, OR
cleantech hardware iot data
ESS Tech manufactures iron flow long-duration energy-storage systems (including its Energy Base platform) for commercial and utility-scale customers, with software for monitoring and controls. Its customers are utilities and large energy buyers. It is a Wilsonville-HQ'd public company (NYSE: GWH) with a local hardware/software engineering org.
may be inactive — last checked Jul 2026
public small modular reactor (SMR) nuclear technology founded 2007 · Portland, OR
cleantech hardware data enterprise
NuScale designs small modular nuclear reactors (the NuScale Power Module) and the engineering/software to deploy and control them for carbon-free power. Its customers are utilities and large energy buyers. It is a Portland-HQ'd public company (NYSE: SMR) with a large nuclear and controls engineering org.
growth commercial IoT edge & device certification founded 2010 · 30-60 people · Portland, OR
iot cloud security enterprise data hardware
Rigado provides commercial IoT edge infrastructure - gateways/access points (Cascade 5000) plus a device-certification program ('Rigado Ready') for a unified retail IoT network handling connectivity, edge compute, and security. Customers are retailers and IoT device makers. It is a Portland-HQ'd hardware/software IoT company that has narrowed its focus toward retail IoT.
Latest round: growth · $25M total raised
Founders: Justin Rigling, Ben Corrado
growth telecom payment processing & fraud prevention founded 1995 · 350-400 people · Lake Oswego, OR
fintech payments ai ml security compliance data
Vesta is a telecom-focused payment-processing and fraud-prevention company that uses AI/ML risk decisioning and smart routing to approve more card-not-present transactions while guaranteeing against fraud and chargebacks. Its customers are telecom carriers and MVNOs (AT&T, Vodafone, Rogers, Telcel). It is a mature, PE-controlled company HQ'd in Lake Oswego with a real engineering org.
Leadership: Todd Curry (CEO), Jeff Browning (CTO)
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growth nickel-zinc battery power systems founded 2016 · 150-250 people · Tualatin, OR
cleantech hardware iot data
ZincFive designs and manufactures nickel-zinc (NiZn) battery-based backup/immediate power systems (UPS cabinets, monobloc batteries, cells) with a non-flammable, recyclable chemistry, targeting data centers and AI infrastructure. Its customers are data-center and critical-power operators. It runs a hardware/chemistry/power-electronics engineering org in Tualatin.